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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 36.36
Human Site: S331 Identified Species: 61.54
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 S331 V Q E N G F L S S L P Y L G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 S331 I Q E N G F L S S L P Y L G S
Dog Lupus familis XP_532204 495 54438 S331 V Q E N G L L S A L P Y F G C
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 S331 V Q E N G F L S A L P Y F G C
Rat Rattus norvegicus Q7TSF2 588 64736 S356 I S K V G L L S A V P H M V M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 S314 S S L K N Q L S T Q K S V P W
Chicken Gallus gallus NP_001026257 484 53539 S320 A Q E N G F L S A L P Y F G C
Frog Xenopus laevis Q6INC8 576 63887 S344 I S K V G L L S A L P H L V M
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 S357 I S K V G I L S A V P H M V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 S336 L K S N G L L S S L P Y L A M
Honey Bee Apis mellifera XP_395682 508 56831 S330 L D K T G F L S A L P Y L A M
Nematode Worm Caenorhab. elegans Q03567 493 52719 A319 V A S I P Y I A Y F L A I N A
Sea Urchin Strong. purpuratus XP_780445 542 58846 S339 I S Q S G F L S A V P Y L V M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 C392 L T E S G L L C V L P W L T M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 93.3 73.3 N.A. 80 26.6 N.A. 13.3 73.3 40 26.6 N.A. 60 53.3 6.6 46.6
P-Site Similarity: 100 N.A. 100 80 N.A. 86.6 66.6 N.A. 26.6 80 66.6 66.6 N.A. 73.3 73.3 40 80
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 8 58 0 0 8 0 15 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 22 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 43 0 0 0 8 0 0 22 0 0 % F
% Gly: 0 0 0 0 86 0 0 0 0 0 0 0 0 36 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 % H
% Ile: 36 0 0 8 0 8 8 0 0 0 0 0 8 0 0 % I
% Lys: 0 8 29 8 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 22 0 8 0 0 36 93 0 0 65 8 0 50 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 50 % M
% Asn: 0 0 0 43 8 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 86 0 0 8 0 % P
% Gln: 0 36 8 0 0 8 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 36 15 15 0 0 0 86 22 0 0 8 0 0 15 % S
% Thr: 0 8 0 8 0 0 0 0 8 0 0 0 0 8 0 % T
% Val: 29 0 0 22 0 0 0 0 8 22 0 0 8 29 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 58 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _